Free Standard Delivery with £60+ spend Speak to a Skincare Specialist Keyworker & Student Discount
Receive a complimentary Try Me Box (worth £97) with £85+ spend. Or purchase for only £21.

Neuropeptide Night Cream

This ultra-rich night cream visibly and dramatically softens the appearance of deep lines and creases by deeply nourishing and hydrating.

£210.00

Or 3 interest free payments of £70.00 with clearpay


Frequently Bought Together

Other Customers Bought

Customer Reviews

4.5

40 reviews

5

4

3

2

1

33

0

3

2

2

Top Customer Reviews

Where reviews refer to foods or cosmetic products, results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Wanted to love this

I appreciate Perricone. The actives & formulations can be effective. I've seen results with other products, so I splurged after reading reviews. I'm 51 & looking for something that addresses all of my concerns- wrinkles/creases, pores/texture, and loss of firmness around jawline/chin. This product had a lot of promise & I bought it specifically due to the DMAE. Used it consistently for 30 days. It did lighten a prominent crease in my forehead and I think some improvement in firmness, but did nothing for creases at the corners of my mouth or gravitational wrinkles on my chin. These lines are still in a soft category, but I still saw no improvement whatsoever. It also caused deep cystic acne outbreaks between my lip and chin. Its a very greasy formula, it practically melts into an oil from the heat of your skin. I tried to return but they only accept unopened product. I will not buy direct from their website again. Another product that I received with my order was set to expire in JUNE(3 months). They are replacing it. Just a warning to check your expiration dates.

by Patricia Verified Purchase

Was this helpful?

Silky

I bought this cream wanting to try this line. It is thick but not too thick. It melts into my skin beautifully. No heavy scent and the moisture lasts.

by Teresa Verified Purchase

Was this helpful?

Love Perricone

I've been using Perricone for 20 years and the results are amazing. Love Perricone

by Sylvia Verified Purchase

Was this helpful?

Nighttime Facial cream

Just love this facial cream! It is smooth, applies beautifully and is a wonderful deep overnight moisturizer. 

by Eloyce Verified Purchase

Was this helpful?

Totally Works!

I have ALL Perricone skincare! After I use up the subD serum, am staying with the C and Retinol and THIS! It literally has changed my face! In one application I saw a difference! So I ordered the day one too! It even works on my eyes! The BEST anti-aging cream I EVER used and I am 68! Its worth every nickel, especially with the new payment plans. And it takes such a small amount too. It works on my neck too! Great product, is a holy trail for sure!

by Becca68 Verified Purchase

Was this helpful?

Totally Works!I

I switched skincare lines since I'm older now. Felt I needed something stronger at 68. Always wanted to try this line and thanks to Afterpay and Klarna, I have been able to. This is my last purchase for awhile as I have the two serums and another on the way, face finishing moisturizer, deep crease serum,sub d neck cream and more. This has totally changed my skin. I don't look forty, but my skin looks great, wrinkles are literally disappearing. My neck looks so much better. But it has taken about three months,which is fine with me. I didn't get these in a month. It took years. This cream just puts the finishing touch on it all. Thank you.

by Becca68 Verified Purchase

Was this helpful?

My new nighttime ritual

My first experience with the neuropeptide products was the facial cream. I was so impressed after a few months that I added this to my skincare routine. My first tube separated, meaning I had to shake it vigorously before squirting any out or I would only get oil. When the tube was almost empty I cut it open and found the rich, emollient cream in the bottom of the tube. Knowing that Perricone products dont have the greatest shelf life, I tried a second tube and it was perfect. You need to watch for this, Perricone! This is an expensive product; however, its a good one. I love what the combo of the day and night cream has done. My skin sensitivity is gone and my skin appears thicker. At age 64, with a thin face, I need all the help I can get to plump up my skin. I dont need an additional nighttime moisturizer. This cream is enough.

by Elmel Verified Purchase

Was this helpful?

Great moisturizer!

This cream is the best moisturizer I found on the market. Im 45 years old and need a cream that addresses dryness and fine lines. This cream is simply amazing. It gives me a beautiful glow as well. I use it in the morning under my makeup when I need extra hydration. I highly recommend it!

by Classicbeauty Verified Purchase

Was this helpful?

Be aware do not use this product

Nothing is good about it . I am in to my 5 th week from stopping using this cream and it feels like someone has poured acid over my face . It's bright red/ burning / itching / dry and tight And flaking. I am under the doctor at the moment for this bad reaction it hasn't got any better from start to finish . Well there is no finish it's still bad 5 weeks on .

by Rose

Was this helpful?

I will definitely buy again

I love this moisturizer, I use it every night after I wash my face. It's got a thick texture but blends so well at the same time. My skin has definitely improved since I started using Perricone. I'm almost 50 and my skin is pretty healthy.

by Dara Verified Purchase

Was this helpful?